Selection – Communicable Diseases Research

Identification and characterization of the anti-SARS-CoV-2 activity of cationic amphiphilic steroidal compounds

양이온성 양친매성 스테로이드 화합물의 항 SARS-CoV-2 활성의 확인 및 특성화

Article

Published on 2022-12-012022-09-11
Journal: Virulence
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, 치료제,

Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational study

Article

Published on 2022-11-072022-11-15
Journal: BMJ Open
[Category] SARS, 변종, 진단,

[키워드] 95% CI Analysis assessment behavioural COVID-19 demographic Diseases effective enhanced enrolled Epidemiology Factor General population HCW HCWs Health healthcare Healthcare system healthcare worker higher risk highest hospital identify include Infection infection control investigated Logistic regression measure multivariate logistic regression Observational cohort study occupational Pandemics Personal protective equipment Physiotherapist positive PPE Public public health. questionnaire Regression model Reporting Resilience retrospective risk risk factor risk reduction SARS-CoV-2 antibody SARS-COV-2 infection SARS-CoV-2 variant Selection Shrinkage social distancing social distancing measures stability sustained Vaccine variable was used Workplace
[DOI] 10.1136/bmjopen-2022-063159 PMC 바로가기

RASCL: Rapid Assessment of Selection in CLades through molecular sequence analysis

Article

Published on 2022-11-022022-11-16
Journal: PLoS ONE
[Category] SARS, 변종, 치료기술,

Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2

Article

Published on 2022-10-212022-11-15
Journal: ACS chemical biology
[Category] COVID19(2023년), SARS, 치료기술, 치료제,

Importance of Intermittent Fasting Regimens and Selection of Adequate Therapy on Inflammation and Oxidative Stress in SARS-CoV-2 Infection

Article

Published on 2022-10-142022-11-16
Journal: Nutrients
[Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome Adequate approach cancers cardiovascular disease chronic disease Chronic diseases communicable disease complementary coronavirus COVID-19 CVD Diabetes Mellitus dietary dietary supplements effective fasting fatty acids feasible hallmark immunomodulatory Importance Inflammation Inflammatory Intermittent intermittent fasting Modification nutraceutical obesity outcome oxidative oxidative stress Patient Polyunsaturated Post-infection quercetin Randomized controlled trial regimen SARS-CoV-2 Selection severe coronavirus disease suggested systemic Therapies time-restricted eating Treatment variant Vitamin vitamins vitamins. was performed
[DOI] 10.3390/nu14204299 PMC 바로가기

Deep mutational learning predicts ACE2 binding and antibody escape to combinatorial mutations in the SARS-CoV-2 receptor-binding domain

Article

Published on 2022-10-132022-11-15
Journal: Cell
[Category] COVID19(2023년), SARS, 변종, 진단,

Blood Endothelial-Cell Extracellular Vesicles as Potential Biomarkers for the Selection of Plasma in COVID-19 Convalescent Plasma Therapy

Article

Published on 2022-10-042022-11-15
Journal: Cells
[Category] 바이오마커,

[키워드] Activation age anti-SARS-CoV-2 antibody Biomarkers Blood blood endothelium cardiovascular disease caused CCP CCP therapy Characteristics characterized clinical symptom Concentration consequence convalescent plasma Convalescent plasma therapy coronavirus disease COVID-19 death Donor downregulation Endothelial cell Endothelial dysfunction Endothelium evidenced excessive inflammation expected extracellular vesicle Extracellular vesicles extracellular vesicles. hospital ICAM1 identify individual infected individual inflammatory storm massive secretion mechanism mild symptoms mitochondrial dysfunction multi-organ failure onset of symptom overexpression parameter Peripheral blood plasma Potential pro-inflammatory pro-inflammatory cytokine progression promoted reflected selected Selection severity subset Symptoms the disease therapy vaccination Vascular endothelium vascular inflammation vessel was increased
[DOI] 10.3390/cells11193122 PMC 바로가기

New Chemicals Suppressing SARS-CoV-2 Replication in Cell Culture

Article

Published on 2022-09-052022-11-15
Journal: Molecules
[Category] SARS, 치료제,

How I treat and prevent COVID-19 in patients with hematologic malignancies and recipients of cellular therapies

혈액암 환자와 세포 요법을 받는 환자의 COVID-19 치료 및 예방 방법

Article

Published on 2022-08-182022-09-11
Journal: Blood
[Category] SARS, 변종, 임상, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration approach attenuate breakthrough infections Cell Cell therapy cell transplantation cellular therapy circulating circulating SARS-CoV-2 variants Clinical efficacy coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 in patient COVID-19 vaccine COVID-19 vaccines Drug-drug interactions Factors General population HCT Hematologic malignancy Hematopoietic cell transplantation higher risk Host Humoral response increased risk Infection morbidity morbidity and mortality Patient Postexposure Prophylaxis practicality Prevent progression recipient recipients SARS-CoV-2 Selection severe acute respiratory syndrome Coronavirus severe coronavirus disease severe COVID-19 Side effects therapeutic Therapies therapy treat Treatment virus
[DOI] 10.1182/blood.2022016089 PMC 바로가기 [Article Type] Article

Selection of Bis-Indolyl Pyridines and Triphenylamines as New Inhibitors of SARS-CoV-2 Cellular Entry by Modulating the Spike Protein/ACE2 Interfaces

스파이크 단백질/ACE2 인터페이스를 조절하여 SARS-CoV-2 세포 진입의 새로운 억제제로서 비스-인돌릴 피리딘 및 트리페닐아민 선택

Article

Published on 2022-08-162022-09-11
Journal: Antimicrobial Agents and Chemotherapy
[Category] COVID19(2023년), SARS, 변종,

[키워드] 50% effective concentration ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus approaches association biochemical caused Cell cell lines cellular cellular receptor circulating circulating variant complex Compound coronavirus coronavirus disease COVID COVID-19 docking drug functional human cell lines identify in silico indicate Infection infectious agent inhibit inhibitor inhibitory inhibitory effect Interaction interface Lentiviral vector lentiviral vectors modulating molecular molecules New pandemic parameter pseudotyped pyridine receptor ACE2 S protein SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 S protein SARS-CoV-2 strain screened selected Selection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 spike susceptible the SARS-CoV-2 the Spike therapeutic purposes these compound these compounds triphenylamine variant viral entry viral entry. viral infection viral replication virus wild-type
[DOI] 10.1128/aac.00083-22 PMC 바로가기 [Article Type] Article